An efficient synthesis of 2-amino-5-chloro-3-pyridinecarbox-aldehyde and 5-amino-2-chloro-4-pyridinecarboxaldehyde

Heterocyclic communications

article

Chuan-Jin Hou¹  Wei-Lei Guo¹  Xiao-Ning Liu¹  Da-Wei Yang¹ 

[1] School of Chemicals and Materials, Dalian Polytechnic University;Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture

关键词: amino;    chloro;    naphthyridine;    pyridinecarbox-aldehyde;    synthesis;   

DOI  :  10.1515/hc.2011.004

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

Efficient synthetic routes to the title compounds 2-amino-5-chloro-3-pyridinecarboxaldehyde (1a) and 5-amino-2-chloro-4-pyridinecarboxaldehyde (1b) are reported. Both compounds are important substrates in the synthesis of naphthyridine derivatives.

【 授权许可】

CC BY|CC BY-NC-ND