Iodine-catalyzed synthesis of 5-arylanthra[2,1-c][2,7]naphthyridine derivatives via three-component reaction

Heterocyclic communications

article

Hong Jiang¹  Wei Wang²  Xiang-Shan Wang² 

[1] The Key Laboratory of Biotechnology on Medical Plant of Jiangsu Province, Jiangsu Normal University;School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University

关键词: anthracen-2-amine;    iodine;    naphthyridine;    synthesis.;   

DOI  :  10.1515/hc-2012-0043

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A series of ethyl 5-aryl-1,2-dihydroanthra[2,1- c ][2,7]naphthyridine-3(4 H )-carboxylate derivatives was prepared by a three-component reaction of aromatic aldehyde, anthracen-2-amine and ethyl 4-oxopiperidine-1-carboxylate using iodine as catalyst. This iodine-catalyzed procedure has the advantages of mild reaction conditions, good yields, operational simplicity and metal-free catalyst.

【 授权许可】

CC BY|CC BY-NC-ND