Synthesis of [1,3]thiazolo[3,2-b][1,2,4]triazol-7-ium and [1,2,4]triazolo[5,1-b][1,3]thiazin-4-ium salts via regioselective electrophilic cyclization of 3-[(2-alken-1-yl)sulfanyl]-4H-1,2,4-triazoles

Heterocyclic communications

article

Mikhailo Slivka¹  Nataliya Korol¹  Ivan Rusyn¹  Vasyl Lendel¹ 

[1] Organic Synthesis Laboratory, Uzhhorod National University

关键词: electrophilic cyclization;    halogen;    regioselectivity;    selenium tetrahalogenides;    tellurium tetrahalogenides;    [1;    3]thiazolo[3;    2-b][1;    2;    4]triazol-7-ium;    [1;    2;    4]triazolo[5;    1-b][1;    3]thiazin-4-ium;   

DOI  :  10.1515/hc-2015-0158

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A convenient procedure for the regioselective preparation of [1,3]thiazolo[3,2- b ][1,2,4]triazol-7-ium 10 and [1,2,4]triazolo[5,1- b ][1,3]thiazin-4-ium salts 9 via regioselective electrophilic cyclization of 3-[(2-alken-1-yl)sulfanyl]-4 H -1,2,4-triazoles 3 is reported. Direction of electrophilic heterocyclization strongly depends on nature of the alkenyl substitutent.

【 授权许可】

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