Visible-light-mediated radical aryltrichloromethylation of N-arylacrylamides for the synthesis of trichloromethyl-containing oxindoles

Heterocyclic communications

article

Mei Zhu¹  Weijun Fu¹ 

[1] College of Chemistry and Chemical Engineering, Luoyang Normal University

关键词: alkenes;    aryltrichloromethylation;    oxindole;    photoredox;    radical reactions;   

DOI  :  10.1515/hc-2015-0097

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A practical and unified strategy has been described for the construction of trichloromethylated oxindoles via a visible light-promoted aryltrichloromethylation reaction of N -arylacrylamides with tetrachloromethane. These reactions are carried out at room temperature in good to excellent chemical yields with good functional group tolerance.

【 授权许可】

CC BY|CC BY-NC-ND