Photo-induced catalytic C−H heteroarylation of group 8 metallocenes

Cell Reports Physical Science

Shi-Yu Guo¹  Ying Li¹  Ding-Wei Ji¹  Hao Zheng²  Gu-Cheng He²  Chang-Hui Liu²  Xiang-Ting Min²  Qing-An Chen² 

[1] University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China;Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, People’s Republic of China;

关键词: ferrocene;    ruthenocene;    C-H heteroarylation;    photoredox;    radical reaction;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: Possessing a characteristic sandwich-type structure, metallocenes have been widely used by the chemistry community. However, the direct catalytic C−H heteroarylation of metallocenes still remains underexplored. Here, we report an efficient catalytic protocol for C−H heteroarylation of group 8 metallocenes (M = Fe, Ru) under light irradiation. This intermolecular cross coupling features directing group free, mild conditions and a wide substrate scope. Preliminary mechanistic studies suggest that the newly formed C−C bond is constructed through electrophilic radical substitution of the metallocene with a heteroaryl radical, which is generated via an oxidative quenching pathway.

【 授权许可】

Unknown