Synthesis of 7-cyanoindolizine derivatives via a tandem reaction

Heterocyclic communications

article

Xian-Sheng Zhang¹  Bin Wang¹  Jiong Jia¹  Yan-Qing Ge²  Jianwu Wang¹ 

[1] School of Chemistry and Chemical Engineering, Shandong University;School of Chemical Engineering, Taishan Medical University

关键词: 4-bromobut-2-enenitrile;    indolizine;    one-pot;    pyrrole-2-carboxaldehyde;   

DOI  :  10.1515/hc-2016-0223

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

Abstract: A series of 2-substituted and 2,3-disubstituted 5-cyanoindolizine derivatives were conveniently synthesized by a one-pot tandem reaction under mild conditions in moderate yields. The reaction mechanism was proposed.

【 授权许可】

CC BY|CC BY-NC-ND