Methyl 3-(Quinolin-2-yl)indolizine-1-carboxylate

Molbank

Roumaissa Belguedj¹  Esma Lamera¹  Abdelmalek Bouraiou¹  Zouhair Bouaziz²  Aissa Chibani¹ 

[1] Unité de Recherche de Chimie de l’Environnement et Moléculaire Structurale, Université Frères Mentouri, Constantine 25000, Algeria;ISPB, EA 4446 Biomolécules Cancer et Chimiorésistances, SFR Santé Lyon-Est CNRS UMS3453-INSERM US7, Faculté de Pharmacie, Université Lyon 1, 8 Avenue Rockefeller, F-69373 Lyon Cedex 8, France;

关键词: quinoline;    cycloaddition;    indolizine;   

DOI  :  10.3390/M883

来源: mdpi

【 摘 要 】

A novel compound, methyl 3-(quinolin-2-yl)indolizine-1-carboxylate (2) has been synthesized by cycloaddition reaction of 1-(quinolin-2-ylmethyl)pyridinium ylide (1) with methyl propiolate in presence of sodium hydride in THF. The structure of this compound was established by IR, ¹H-NMR, ¹³C-NMR and MS data.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.