A simple one-pot synthesis of 2,4-diaryl- 9H-pyrido[2,3-b]indoles under solvent-free conditions

Heterocyclic communications

article

Mehdi Khoshneviszadeh¹  Aida Yahagh²  Mehdi Soheilizad²  Mohammad Mahdavi³ 

[1] Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences;School of Chemistry, College of Science, University of Tehran;Drug Design and Development Research Center, Tehran University of Medical Sciences

关键词: ammonium acetate;    chalcones;    heterocycles;    oxindoles;    solvent-free;    9H-pyrido[2;    3-b]indoles;   

DOI  :  10.1515/hc-2016-0222

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A novel, simple, one-pot synthesis of 2,4-diaryl-9 H -pyrido[2,3- b ]indoles is described. Heating a mixture of chalcone, oxindole and ammonium acetate in the presence of potassium tert -butoxide under solvent-free conditions afforded the title compounds in good to excellent yields.

【 授权许可】

CC BY|CC BY-NC-ND