Synthesis of ferrocenyl oxindole compounds with potential anticancer activity

Journal of the Brazilian Chemical Society

Silva, Bárbara V.¹  Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil¹  Vargas, Maria D.¹  Universidade Federal Fluminense, Niterói, Brazil¹  Pinto, Angelo C.¹  University of Campinas, Campinas, Brazil¹  Dias, Luiz C.¹  Ribeiro, Núbia M.¹ 

关键词: ferrocenyl oxindoles;    oxindoles;    ferrocenecarboxyaldehyde;   

DOI  :  10.1590/S0103-50532008000700003

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A series of ferrocenyl oxindoles with potential anticancer activity were prepared from the reactions of substituted oxindoles and ferrocenylcarboxyaldehyde in the presence of KOH as catalyst. The products were characterized by spectral data including 1H and 13C NMR, IR and mass spectrometry. The E and Z configurations were established by nOe or NOESY experiments.

【 授权许可】

Unknown