Synthesis of ferrocenyl oxindole compounds with potential anticancer activity

Journal of the Brazilian Chemical Society

Bárbara V. Silva²  Núbia M. Ribeiro²  Angelo C. Pinto²  Maria D. Vargas¹  Luiz C. Dias¹ 

[1] ,Universidade Federal do Rio de Janeiro Instituto de Química Rio de Janeiro RJ ,Brazil

关键词: ferrocenyl oxindoles;    oxindoles;    ferrocenecarboxyaldehyde;   

DOI  :  10.1590/S0103-50532008000700003

来源: SciELO

【 摘 要 】

A series of ferrocenyl oxindoles with potential anticancer activity were prepared from the reactions of substituted oxindoles and ferrocenylcarboxyaldehyde in the presence of KOH as catalyst. The products were characterized by spectral data including ¹H and 13C NMR, IR and mass spectrometry. The E and Z configurations were established by nOe or NOESY experiments.

【 授权许可】

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