Visible light mediated aerobic oxidative hydroxylation of 2-oxindole-3-carboxylate esters: an alternative approach to 3-hydroxy-2-oxindoles

Heterocyclic communications

article

Jinge Wang¹  Siyitemer Osman¹  Xinjiang Lu¹  Junyi Chen¹  Xu-Dong Xia¹ 

[1] Engineering Laboratory of Chemical Resources Utilization in South Xinjiang of Xinjiang Production and Construction Corps, College of Life Sciences, Tarim University

关键词: Visible light;    Photocatalysis;    Oxindole;    Aerobic oxidation;   

DOI  :  10.1515/hc-2019-0114

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A convenient aerobic oxidative hydroxylation of 3-substituted oxindoles under mild reaction conditions is described herein. This process was accomplished by the activation of molecular oxygen in the air in the presence of a photocatalyst under the irradiation of visible light. The desired product was delivered in up to 89% yield without the addition of base or stoichiometric oxidant.

【 授权许可】

CC BY|CC BY-NC-ND