Case Report: Insulin-Dependent Diabetes Mellitus and Diabetic Keto-Acidosis in a Child With COVID-19

Frontiers in Pediatrics

Adriana Martinez Olivera¹  Yonca Bulut²  Erica Li²  Karin Nielsen-Saines³  Rachel Martin-Blais³ 

[1] Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;Division of Critical Care Medicine, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;Division of Pediatric Infectious Diseases, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;

关键词: COVID-19;    children;    type 1 diabetes mellitus (T1DM);    diabetic keto-acidosis (DKA);    SARS CoV-2;    pediatric COVID-19;   

DOI  :  10.3389/fped.2021.628810

来源: Frontiers

【 摘 要 】

During the COVID pandemic, a surge in pediatric Type 1 Diabetes Mellitus (T1DM) cases appears to be occurring, potentially due to the presence of autoantibody-induced immune dysregulation triggered by COVID-19. We describe one such case in a previously healthy 7-year-old with asymptomatic COVID-19 presenting with a high nasopharyngeal SARS CoV-2 virus load, detectable COVID-19 IgG antibodies, diabetic keto-acidosis and islet cell autoantibodies. COVID-19 is not a trivial disease in children and adolescents and can lead to lifelong sequelae such as T1DM. Raising awareness about a possible association between COVID-19 and T1DM in children is critical.

【 授权许可】

CC BY