The prevalence of depression among parents of children/adolescents with type 1 diabetes: A systematic review and meta-analysis

Frontiers in Endocrinology

Endocrinology

Ciriaco Carru¹  Donatella Coradduzza¹  Zhichao Chen²  Jing Wang³  Zhi Li⁴ 

[1] Department of Biomedical Sciences, University of Sassari, Sassari, Italy;Department of Biomedical Sciences, University of Sassari, Sassari, Italy;Department of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China;Department of Biomedical Sciences, University of Sassari, Sassari, Italy;Department of Obstetrics and Gynecology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China;Department of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China;

关键词: parental depression;    parental mental illness;    type 1 diabetes mellitus (T1DM);    children;    adolescents;    systematic review and meta-analysis;   

DOI  :  10.3389/fendo.2023.1095729

 received in 2022-11-11, accepted in 2023-02-14,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundEmerging research indicates that depression among parents of children/adolescents with type 1 diabetes mellitus (T1DM) has increased significantly. However, the prevalence rates reported by different studies vary substantially.MethodsSeven databases were systematically searched (Pubmed, Embase, MEDLINE, Scopus, Web of Science, Cochrane Library, PsycInfo) from the inception to 15th October 2022. We pooled prevalence rates from each study with a random-effect model. We conducted a stratified meta-analysis to identify the potential sources of heterogeneity among studies. The GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach was utilized to evaluate the quality of evidence.ResultsTwenty-two studies were included, with a total of 4639 parents living with type 1 diabetic children. Overall, the pooled prevalence rate of depression or depressive symptoms was 22.4% (95%CI 17.2% to 28.7%; I2 = 96.8%). The prevalence was higher among mothers (31.5%) than fathers (16.3%) as well as parents of children (aged < 12 years) with T1DM (32.3%) than those with adolescents (aged ≥ 12 years) (16.0%).ConclusionOur research suggests that more than 1 in 5 parents of type 1 diabetic children/adolescents worldwide suffer from depression or depressive symptom. Depression screening and interventions are required for parents of children with T1DM.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier (CRD42022368702).

【 授权许可】

Unknown   
Copyright © 2023 Chen, Wang, Carru, Coradduzza and Li