Spontaneous regression of non‐small cell lung cancer that progressed after multiple chemotherapies: A case report

Thoracic Cancer

Chaeuk Chung²  Dong Il Park²  Sun Young Kim²  Ju Ock Kim²  Sung Soo Jung²  Hee Sun Park²  Jae Young Moon²  Sung Min Kim¹  Min Ji Cho²  Sang Ok Jung²  Choong Sik Lee³ 

[1] Department of Nuclear Medicine, College of Medicine, Chungnam National University, Deajeon, Korea;Division of Pulmonology, Department of Internal Medicine, College of Medicine, Chungnam National University, Deajeon, Korea;Department of Pathology, College of Medicine, Chungnam National University, Deajeon, Korea

关键词: Chemotherapy;    non‐small cell lung cancer;    spontaneous neoplasm regression;   

DOI  :  10.1111/1759-7714.12221

来源: Wiley

【 摘 要 】

Abstract

Spontaneous regression (SR) of cancer is defined as a complete or partial, temporary or permanent disappearance of all or at least some relevant parameters of malignant disease with inadequate or no treatment. SR of cancer is an extremely rare phenomenon. We report a case of a 67-year-old man who experienced SR of non-small-cell lung cancer (NSCLC), which progressed after fifth-line chemotherapy and regressed after chemotherapy ceased. Surprisingly, the primary tumor size continued to decrease for more than 13 months and his general condition markedly improved after discontinuation of the chemotherapy. To our knowledge, this is the first report of SR in a patient with NSCLC that was not responsive to a fifth round of chemotherapy.

【 授权许可】

CC BY-NC   
© 2015 The Authors. Thoracic Cancer published by Tianjin Lung Cancer Institute and Wiley Publishing Asia Pty Ltd.

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