Magnetic, Fluorescent, and Copolymeric Silicone Microspheres

Advanced Science

Jacqueline M. Rankin¹  Nitin K. Neelakantan¹  Kimberly E. Lundberg¹  Elissa M. Grzincic¹  Catherine J. Murphy¹ 

[1]Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA

关键词: aerosol polymerization;    drug delivery;    microencapsulation;    polydimethylsiloxane;    sonochemistry;   

DOI  :  10.1002/advs.201500114

来源: Wiley

【 摘 要 】

Abstract

Silicone microspheres are exceedingly difficult to make. Here, polydimethylsiloxane microspheres (≈1 μm diameter) are synthesized using ultrasonic spray pyrolysis, the first demonstration of a scalable synthetic procedure for crosslinked silicone microspheres. This continuous, aerosol process is also used to directly produce fluorescent, magnetic, and copolymeric derivatives; the potential biomedical applications of these microspheres are explored.

【 授权许可】

CC BY   
© 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.