Formation of gold nanoparticle dimers on silicon by sacrificial DNA origami technique

Micro & nano letters

article

Naoki Yamashita¹  Zhipeng Ma¹  Seongsu Park¹  Kentaro Kawai²  Yoshikazu Hirai¹  Toshiyuki Tsuchiya¹  Osamu Tabata¹ 

[1] Department of Microengineering, Graduate School of Engineering, Kyoto University;Department of Precision Science and Technology, Graduate School of Engineering, Osaka University;Freiburg Institute for Advanced Studies, Albert-Ludwigs-University

关键词: gold;    nanoparticles;    silicon;    elemental semiconductors;    self-assembly;    DNA;    molecular biophysics;    nanobiotechnology;    surface enhanced Raman scattering;    biosensors;    nanosensors;    X-ray photoelectron spectra;    gold nanoparticle dimers;    silicon chip;    sacrificial DNA origami technique;    nanogap-based device;    single-molecule label-free detection;    surface-enhanced Raman spectroscopy;    SERS;    self-assembly;    amino-terminated monolayer;    vacuum ultraviolet treatment;    ultrapure water cleaning;    X-ray photoelectron spectroscopy;    EB lithography;    Au-Si;   

DOI  :  10.1049/mnl.2017.0426

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background: Co-administration of small dose of opioids with bupivacaine for spinal analgesia is advocated because of synergistic action between local anaesthetics and opioids, leading to reduction in doses, intraoperative discomfort and postoperative analgesic requirement. Aim: We compared the effects of intrathecal sufentanil with intrathecal morphine, when added to bupivacaine for caesarean sections. Method: Sixty ASA I and II parturients, undergoing caesarean section under spinal anaesthesia, were randomly allocated into three groups of 20 each to receive either injection (inj.) bupivacaine 12 mg (Group I), which was labelled as the control group; inj. bupavacaine 12mg + inj sufentanil 10mcg (Group II) or inj. bupavacaine 12 mg + morphine 0.2mg (Group III) in a double blind clinical trial. The parameters studied were the time of onset, sensory level of the block achieved, total duration of analgesia, any need of rescue analgesics, maternal side effects and foetal outcome..

【 授权许可】

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