Synthesis of novel periodic mesoporous organosilicas with large content of lysine-bridged organosilane skeleton

Micro & nano letters

article

Jianqiang Wang¹  Changqing Gu¹  Man Zhou¹  Wenqi Zhang¹  Zhiwei Wang¹  Mengyuan Lv¹  Cheng Guo¹  Linbing Sun² 

[1] College of Chemistry and Molecular Engineering, Nanjing Tech University;College of Chemical Engineering, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University

关键词: mesoporous materials;    organic compounds;    condensation;    X-ray diffraction;    adsorption;    desorption;    Fourier transform infrared spectra;    nanofabrication;    nanoporous materials;    periodic mesoporous organosilicas;    lysine-bridged organosilane skeleton;    functional nanomaterials;    co-condensation;    lysine-bridged organosilicane;    tetraethyl orthosilicate;    acidic medium;    amino acid organosilicane;    multistep reaction;    traditional orgnaosilicane;    (3-aminopropyl) triethoxysilane;    carboxyl protected lysine;    small-angle X-ray diffraction;    N2 adsorption-desorption ordered mesostructure;    high molar concentration;    Fourier-transform infrared spectroscopy;    N2;   

DOI  :  10.1049/mnl.2017.0202

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Background: Staging for breast cancer patients, as defined by the American Joint Committee on Cancer (AJCC), has historically been limited to anatomical staging. However, the eighth version of the AJCC guidelines has been altered to include tumour biology. Anatomical staging still has a place especially in low-middle income countries where the majority of patients present with locally advanced or metastatic disease. Aim: This review article considers which newly diagnosed breast cancer patients should be referred for anatomical staging and the pros and cons of the different modalities available in South Africa. Method: The different modalities available were reviewed with respect to metastatic screening for asymptomatic women. The usefulness of the modalities were considered with reference to organ-specific disease rather than the stage of the patient. Results: Any person with newly diagnosed breast cancer and symptoms suggestive of systemic involvement should be investigated. All symptomatic women who present with a tumour larger than 5 cm, radiological or clinical evidence of nodal disease, triple negative or HER2+ve tumours should have metastatic screening. This gives information about the primary as well as the metastatic status. Conclusion: However, increasingly, the major determinant of treatment is the biology of the cancer and not the anatomical stage. In future, this trend is likely to increase with anatomical staging becoming less important.

【 授权许可】

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