Comparative and verified studies of zirconium nanocomposite nanofibres by bubble spinning

Micro & nano letters

article

Ya Li¹  Ji-Huan He¹ 

[1]National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University

[2]Jiangsu Wangong Technology Group Co., Ltd.

关键词: nanocomposites;    zirconium compounds;    nanofibres;    filled polymers;    nanofabrication;    porosity;    thermal stability;    tensile strength;    nanomechanics;    zirconium nanocomposite nanofibres;    bubble spinning;    as-spun fibre polymers;    zirconia powder carriers;    thermal property;    pore-size distribution;    theoretical fluid mechanics analyses;    principle structural diagrams;    PAN-based zirconia nanocomposite;    thermal stability;    pore structure;    mechanical property;    surface morphology;    ZrO2;   

DOI  :  10.1049/mnl.2017.0075

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

Objective : To evaluate the adherence to American Society of Clinical Oncology (ASCO) guidelines for antiemetic prophylaxis of chemotherapy-induced nausea and vomiting and assess the outcomes of the prescribed antiemetic drugs. Methods : This prospective, observational study enrolled chemotherapy-naive cancer patients who were admitted to the National Cancer Institute between May and July 2015 for intravenous chemotherapy. Patient’s demographic data, chemotherapy protocols and types of antiemetic drugs were collected by reviewing patients’ files, chemotherapy prescription forms and interviewing the patients. Results : The data revealed that 90% of pre-chemotherapy antiemetic prescriptions did not adhere to antiemetic guidelines. The trends of non-adherence included an overuse of ondansetron (14%), under-prescribing of dexamethasone (16%) and corticosteroid duplication (14%). Regarding antiemetic use for the prevention of delayed emesis, the data showed that 90% of antiemetic prescriptions were non-adherent with ASCO guidelines, with overuse of ondansetron (20%) and metoclopramide (37%) and lack of dexamethasone prescriptions (80%) on days 2 and 3 being the most frequently reported trends. The percentage of patients with complete response (no emesis or rescue therapy) over 5 days post chemotherapy was 36%. Conclusion : The study indicated an extremely low adherence rate to ASCO guidelines for antiemetic prophylaxis of chemotherapy-induced nausea and vomiting. Non-adherence included a trend of both underuse and overuse of indicated antiemetic medications.

【 授权许可】

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