COVID-19 and HIV infection co-pandemics and their impact: a review of the literature

AIDS Research and Therapy

Kiat Ruxrungtham¹  Opass Putcharoen²  Daniel R. Kuritzkes³  Sivaporn Gatechompol⁴  Anchalee Avihingsanon⁴ 

[1] Chula Vaccine Research Center (ChulaVRC)Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;Division of Infectious Disease, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand;Tuberculosis Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;

关键词: COVID-19;    HIV;    Co-infection;    Pathophysiology;    Clinical;    Outcome;   

DOI  :  10.1186/s12981-021-00335-1

来源: Springer

【 摘 要 】

Coronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus on 4 topics: (1) the pathophysiology and host immune response of people infected with both SARS-CoV-2 and HIV, (2) present the clinical manifestations and treatment outcomes of persons with co-infection, (3) assess the impact of antiretroviral HIV drugs among PLWH infected with COVID-19 and (4) evaluate the impact of the COVID-19 pandemic on HIV services.

【 授权许可】

CC BY