Pathophysiology diabetic foot ulcer

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Syafril, S.^1

Division of Endocrine-Metabolic, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia^1

关键词: Chronic wounds;    Clinical signs;    Diabetes mellitus;    Diabetic foot;    Diabetic foot ulcer;    Mechanical stress;    Pathophysiology;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012161/pdf
DOI  :  10.1088/1755-1315/125/1/012161

来源: IOP

【 摘 要 】

Diabetes Mellitus (DM) is known to have many complications. Diabetes and its complications are rapidly becoming the world's most significant cause of morbidity and mortality, and one of the most distressing is Diabetic Foot Ulcer (DFU). Chronic wound complications are a growing concern worldwide, and the effect is a warning to public health and the economy. The etiology of a DFU is multifaceted, and several components cause added together create a sufficient impact on ulceration: neuropathy, vasculopathy, immunopathy, mechanical stress, and neuroarthropathy. There are many classifications of the diabetic foot. About 50% of patients with foot ulcers due to DM present clinical signs of infection. It is essential to manage multifactorial etiology of DFU to get a good outcome.