4-week eicosapentaenoic acid-rich fish oil supplementation partially protects muscular damage following eccentric contractions

Journal of the International Society of Sports Nutrition

Eisuke Ochi¹  Hisashi Ueda²  Ayaka Kato³  Kenichi Yanagimoto³  Yosuke Tsuchiya⁴ 

[1] Faculty of Bioscience and Applied Chemistry, Hosei University, 3-7-2, Kajino, Koganei, 184-8584, Tokyo, Japan;Graduate School of Sports and Health Studies, Hosei University, Tokyo, Japan;Faculty of Health and Medical Science, Teikyo Heisei University, Chiba, Japan;Food Function R&D Center, Nippon Suisan Kaisha, Ltd, Tokyo, Japan;Laboratory of Health and Sports Sciences, Meiji Gakuin University, Kanagawa, Japan;

关键词: Eicosapentaenoic acid;    Omega-3;    Sports nutrition;    Ergogenic aid;    Long‐chain n-3 polyunsaturated fatty acids;    Lengthening;    Muscle function;    Joint flexibility;   

DOI  :  10.1186/s12970-021-00411-x

来源: Springer

【 摘 要 】

BackgroundWe previously showed 8-week of fish oil supplementation attenuated muscle damage. However, the effect of a shorter period of fish oil supplementation is unclear. The present study investigated the effect of fish oil, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), for 4 weeks on muscular damage caused by eccentric contractions (ECCs) of the elbow flexors.MethodsTwenty-two untrained men were recruited in this double-blind, placebo-controlled, parallel design study and the subjects were randomly assigned to the EPA and DHA group (EPA and DHA, n = 11) and placebo group (PL, n = 11). They consumed either EPA 600 mg and DHA 260 mg per day or placebo supplement for 4 weeks prior to exercise. Subjects performed 60 ECCs at 100 % maximal voluntary contraction (MVC) using a dumbbell. Changes in MVC torque, range of motion (ROM), upper arm circumference, muscle soreness, echo intensity, muscle thickness, serum creatine kinase (CK), and interleukin-6 (IL-6) were assessed before exercise; immediately after exercise; and 1, 2, 3, and 5 days after exercise.ResultsROM was significantly higher in the EPA and DHA group than in the PL group immediately after performing ECCs (p < 0.05). No differences between groups were observed in terms of MVC torque, upper arm circumference, muscle soreness, echo intensity, and thickness. A significant difference was observed in serum CK 3 days after ECCs (p < 0.05).ConclusionsWe concluded that shorter period EPA and DHA supplementation benefits joint flexibility and protection of muscle fiber following ECCs.

【 授权许可】

CC BY