Comparative Study of the Antimicrobial Effect of Nanocomposites and Composite Based on Poly(butylene adipate-co-terephthalate) Using Cu and Cu/Cu2O Nanoparticles and CuSO4

Nanoscale Research Letters

D. Rojas¹  M. F. Melendrez¹  C. Montalba²  S. A. Riquelme³  C. Medina⁴  A. F. Jaramillo⁵  G. Sánchez-Sanhueza⁶  E. Pérez-Tijerina⁷  F. Solís-Pomar⁷ 

[1] Advanced Nanocomposites Research Group (GINA), Department of Materials Engineering (DIMAT), Faculty of Engineering, University of Concepción, 270 Edmundo Larenas, Box 160-C, 4070409, Concepción, Chile;Departamento de Tecnologías Industriales, Universidad de Talca, Camino a Los Niches KM 1, Curicó, Chile;Department of Materials Engineering (DIMAT), Faculty of Engineering, University of Concepción, Box 160-C, 270 Edmundo Larenas, 4070409, Concepción, Chile;Department of Mechanical Engineering (DIM), Faculty of Engineering, University of Concepción, 219 Edmundo Larenas, Concepción, Chile;Department of Mechanical Engineering, Universidad de La Frontera, Francisco Salazar 01145, 4780000, Temuco, Chile;Department of Restorative Dentistry, Endodontic Discipline, Faculty of Dentistry, University of Concepción, Concepción, Chile;Nanoscience and Nanotechnology Laboratory, Faculty of Physical-Mathematical Sciences, Universidad Autónoma de Nuevo León, 66451, San Nicolas de los Garza, Nuevo León, México;

关键词: PBAT;    Bio-nanocomposite;    Copper nanoparticles;    Antimicrobial activity;   

DOI  :  10.1186/s11671-019-2987-x

来源: Springer

【 摘 要 】

Nanocomposites and a composite based on poly(butylene adipate-co-terephthalate) (PBAT) were synthesized using commercial copper nanoparticles (Cu-NPs), copper/cuprous oxide nanoparticles (Cu|Cu2O-NPs), and copper sulfate (CuSO4), respectively. The Cu|Cu2O-NPs were synthesized using chemical reduction and characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The synthesis of Cu|Cu2O-NPs yielded a mixture of Cu and Cu2O, with metal Cu having a spherical morphology of approximately 40 nm in diameter and Cu2O with a diameter of 150 nm. To prepare the nanocomposites (NCs) and the composite material (MC), the NPs and the CuSO4 salt were incorporated into the PBAT matrix in concentrations of 1, 3, and 5% p/p via an ex situ method. Fourier transform infrared spectroscopy (FTIR), a tensile test, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and agar diffusion assays were used for structural, thermomechanical, and antimicrobial characterization. Results showed that the reinforcements did not modify the chemical structure of the PBAT and only slightly increased the percentage of crystallization. The mechanical and thermal properties of the PBAT did not change much with the addition of fillers, except for a slight increase in tensile strength and thermal stability, respectively. The agar diffusion antimicrobial assays showed that the NCs and MCs had good inhibitory responses against the nonresistant strains Enterococcus faecalis, Streptococcus mutans, and Staphylococcus aureus. The MCs based on CuSO4 had the highest biocidal effect, even against the resistant bacteria Acinetobacter baumannii.

【 授权许可】

CC BY