Development of hydroxyapatite/polyvinyl alcohol bionanocomposite for prosthesis implants

International Conference on Advances in Metallurgy, Materials and Manufacturing

冶金学;材料科学;机械制造

Karthik, V.^1 ; Pabi, S.K.^2 ; Chowdhury, S. K. Roy^3

Department of Metallurgical Engineering, Government College of Engineering, Salem, Tamil Nadu

636011, India^1

Department of Metallurgical and Materials Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal

721302, India^2

Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal

721302, India^3

关键词: Bio-nanocomposite;    Haemocompatibility;    Hydroxyapatite ceramics;    Hydroxyapatite powder;    Impregnation conditions;    Nano-hydroxyapatite;    Poly (vinyl alcohol) (PVA);    Sintering temperatures;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/314/1/012031/pdf
DOI  :  10.1088/1757-899X/314/1/012031

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

Hydroxyapatite (Ca10(PO4)6(OH)2) has similar structural and chemical properties of natural bone mineral and hence widely used as a bone replacement substitute. Natural bone consists of hydroxyapatite and collagen. For mimicking the natural, in the present work, a sintered porous hydroxyapatite component has been vacuum impregnated with Polyvinyl alcohol (PVA), which has better properties like biocompatibility, biodegradability and water- solubility. Hydroxyapatite powders have been made into nanosize to reduce the melting point and hence the sintering temperature. In the present investigation high energy ball mill is used to produce nano-hydroxyapatite powders in bulk quantity by optimizing the milling parameters using stainless steel grinding media. Pellets of 10 mm diameter have been produced from nano- hydroxyapatite powders under different uniaxial compaction pressures. The pellets have been sintered to form porous compacts. The vacuum impregnation of sintered pallets with PVA solution of different strength has been done to find the optimum impregnation condition. Microhardness, compressive strength, wear loss and haemocompatibility of hydroxyapatite ceramics have been studied before and after impregnation of PVA. The nano- hydroxyapatite/PVA composites have superior mechanical properties and reduced wear loss than the non-impregnated porous nano-hydroxyapatite ceramics.