Effect of coronary artery bypass grafting on blood pressure response to head-up tilting

The journal of physiological sciences

article

Shinnosuke Hori¹  Yoshi-ichiro Kamijo¹  Mitsuru Yuzaki²  Tetsuya Kawabe³  Kohei Minami¹  Yasunori Umemoto¹  Mao Yokoyama⁴  Hiroyasu Uenishi¹  Yoshiharu Nishimura²  Ken Kouda¹  Yukio Mikami¹  Fumihiro Tajima¹ 

[1] Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine;Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University, School of Medicine;Department of Center for Educational Research and Development, Wakayama Medical University, School of Medicine;Department of Cardiovascular Medicine, Wakayama Medical University, School of Medicine

关键词: Body fluid;    Myocardial infarction;    Angina pectoris;    Rehabilitation;   

DOI  :  10.1186/s12576-020-00746-1

来源: Springer

【 摘 要 】

Blood pressure response to head-up tilt (HUT) in 7 healthy subjects and 9 patients before and after coronary artery bypass grafting (CABG) was measured during supine and 15-min 60° HUT. Stroke volume (SV) and ejection fraction (EF) were assessed by echocardiography. Baseline mean arterial pressure (MAP) and heart rate (HR) in patients before CABG were similar to healthy subjects. MAP in patients decreased by 6 (4–9) mmHg [median (1st–3rd quartiles)] during 7–12 mmHg of HUT with decreased cardiac output (CO = SV × HR) while HR remained unchanged. MAP in healthy subjects remained unchanged during HUT with increased HR. Body weight decreased by 3.5 (2.5–3.7) kg and MAP decreased by 6 (2–13) mmHg during the last 3-min HUT while HR increased after CABG. Decreases in SV and CO during HUT disappeared after CABG. Blood pressure decreased during HUT in patients before and after CABG regardless of HR response.

【 授权许可】

Unknown