Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation

BMC Medical Genomics

Thomas Kirchner¹  Jörg Kumbrink¹  Andreas Jung¹  Wolfgang Goering²  Irene Esposito²  Nicole Pfarr³  Wilko Weichert³  Axel M. Hillmer⁴  Janna Siemanowski⁴  Svenja Wagener-Ryczek⁴  Roberto Pappesch⁴  Jan Rehker⁴  Carina Heydt⁴  Reinhard Buettner⁴  Sabine Merkelbach-Bruse⁴  Christina B. Wölwer⁴  Oscar Velazquez Camacho⁴  Florian Haller⁵  Abbas Agaimy⁵  Karl Worm⁶  Thomas Herold⁶ 

[1] Institute of Pathology, LMU Munich, Munich, Germany;Institute of Pathology, Medical Faculty, Heinrich-Heine-University and University Hospital Duesseldorf, Düesseldorf, Germany;Institute of Pathology, Technical University Munich (TUM), Munich, Germany;Institute of Pathology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany;Institute of Pathology, University Hospital Erlangen, Erlangen, Germany;Institute of Pathology, University Hospital Essen, University Duisburg-Essen, Essen, Germany;

关键词: NGS;    FISH;    Gene fusion;    DNA-Seq;    RNA-seq;   

DOI  :  10.1186/s12920-021-00909-y

来源: Springer

【 授权许可】

CC BY