Development of Polymeric Nanoparticles for Blood–Brain Barrier Transfer—Strategies and Challenges

Advanced Science

Weisen Zhang¹  Ziqiu Tong¹  Lars Esser²  Nicolas H. Voelcker³  Ami Mehta⁴ 

[1] Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia;Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia;Commonwealth Scientific and Industrial Research Organisation (CSIRO), Clayton, VIC, 3168, Australia;Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia;Commonwealth Scientific and Industrial Research Organisation (CSIRO), Clayton, VIC, 3168, Australia;Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, Clayton, VIC, 3168, Australia;Department of Materials Science and Engineering, Monash University, Clayton, VIC, 3800, Australia;Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia;IITB Monash Research Academy, Bombay, Mumbai, 400076, India;

关键词: blood–brain barrier;    drug delivery systems;    microfluidic chips;    neurological diseases;    polymeric nanoparticles;   

DOI  :  10.1002/advs.202003937

来源: Wiley

【 授权许可】

CC BY