Clinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, China

BMC Infectious Diseases

Gangqiang Sun¹  Liang Hong²  Jiguang Ding²  Yanghe Wu²  Shengguo Zhang²  Fujing Cai²  Qingfeng Sun²  Enling Ye³  Xiangao Xie⁴  Shichun Xia⁵  Ling Dong⁶  Renguo Zhao⁶  Xixian Lou⁶  Xiaoyang Wang⁷  Xudong Zheng⁸  Zhanwei Ruan⁸  Yongqi Hu⁸ 

[1] Department of Biology, Gordon College, 01984, Wenham, MA, USA;Department of Infectious diseases, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 108 Wansong Road, Ruian, 325200, Wenzhou, Zhejiang Province, China;Endocrinology Department, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 325200, Ruian City, Zhejiang Province, China;Health bureau of Ruian City, 333 Ruihu Road, Ruian, 325200, Wenzhou, Zhejiang Province, China;Hospital Office, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 325200, Ruian City, Zhejiang Province, China;Pneumology Department, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 325200, Ruian City, Zhejiang Province, China;Radiography Department, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 325200, Ruian City, Zhejiang Province, China;The Emergency Department, the Third Affiliated Hospital to Wenzhou Medical University (Ruian People’s Hospital), 325200, Ruian City, Zhejiang Province, China;

关键词: COVID-19;    Clinical;    Radiographic characteristics;    SARS-cov-2;    Epidemiology;   

DOI  :  10.1186/s12879-020-05528-z

来源: Springer

【 摘 要 】

BackgroundCoronavirus disease 2019 (COVID-19) is an emerging viral disease. Here, we report the clinical features, management, and short-term outcomes of COVID-19 patients in Wenzhou, China, an area outside Wuhan.MethodsPatients admitted to the Infectious Diseases Department of Ruian People’s Hospital in Wenzhou, from January 21 to February 7, 2020, were recruited. Medical data on epidemiological history, demographics, clinical characteristics, laboratory tests, chest computerized tomography (CT) examination, treatment, and short-term outcomes were retrospectively reviewed. Blood biochemistry and routine tests were examined using standard methods and automatic machines. CT examination was performed several times during hospitalization as necessary.ResultsA total of 67 confirmed COVID-19 cases were diagnosed; 64 (95.4%) were common cases and three (4.5%) were severe cases. The most common symptoms at admission were fever (86.6%), cough (77.6%), productive cough (52.2%), chest distress (17.9%), and sore throat (11.9%), followed by diarrhea (7.4%), headache (7.4%), shortness of breath (6.0%), dizziness (4.5%), muscular soreness (4.5%), and running nose (4.5%). Thirty patients (47.8%) had increased C-reactive protein levels. The CT radiographs at admission showed abnormal findings in 54 (80.6%) patients. The patients were treated mainly by oxygen therapy and antiviral drugs. By March 3, 2020, all 67 patients completely recovered and had negative nucleic acid tests. The patients were discharged from the hospital and transferred to a medical observation isolation center for further observation.ConclusionCases of COVID-19 in Wenzhou are milder and have a better prognosis, compared to those in Wuhan. Timely and appropriate screening, diagnosis, and treatment are the key to achieve good outcomes.

【 授权许可】

CC BY