Short-term changes in the anterior segment and retina after small incision lenticule extraction

BMC Ophthalmology

Yue Sun¹  Huaping Liao¹  Yanwei Chen¹  Xi Shen¹ 

[1] Department of Ophthalmology, Ruijin Hospital Affiliated Shanghai Jiao Tong University, School of Medicine, Shanghai, China;

关键词: Small incision lenticule extraction;    Anterior segment;    Retina;    Optical coherence tomography angiography (OCTA);   

DOI  :  10.1186/s12886-020-01668-7

来源: Springer

【 摘 要 】

BackgroundTo analyse short-term changes in the anterior segment and retina after small incision lenticule extraction (SMILE).MethodsPatients with myopia scheduled for SMILE were recruited from Ruijin Hospital, Shanghai, China. Basic patient information such as age, sex, and refractive errors was recorded. Ocular measurements were taken before surgery, and 1 day and 1 week after surgery; they included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, and optic disc vessel density.ResultsSixty-one eyes of 31 patients were selected for this study. AL, CCT, ACD, and postoperative PD were significantly reduced (p < 0.05), while LT was thickened after surgery (p < 0.05). MT at the fovea decreased 1 day and 1 week after surgery (p < 0.05). GCL showed no significant changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was thicker at the fovea 1 day after surgery and 1.0 mm from the fovea in the nasal sector 1 week after surgery. Macular vessel density was significantly decreased 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part 1 day after surgery and recovered after 1 week. ΔACD and ΔLT showed no significant correlation 1 day after surgery. ΔACD was negatively correlated with ΔLT and sphere 1 week after surgery (r = − 0.847, p < 0.000; r = − 0.398, p = 0.002). ΔLT was positively correlated with the sphere 1 week after surgery (r = 0.256, p = 0.048).ConclusionThe anterior segment was the most affected, while the retina also underwent changes with regard to MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

【 授权许可】

CC BY