AIDS by mother-to-child transmission: survival analysis of cases followed from 1983 to 2002 in different regions of Brazil

Cadernos de Saúde Pública

Luiza Harunari Matida²  Alberto Novaes Ramos Jr.¹  José Eduardo Cajado Moncau¹  Luiz Francisco Marcopito¹  Heloisa Helena De Sousa Marques¹  Regina Célia Menezes Succi¹  Marinella Della Negra¹  Norman Hearst¹ 

[1] ,Secretaria Estadual da Saúde Coordenação Estadual de DST/AIDS de São Paulo São Paulo,Brasil

关键词: Vertical Disease Transmission;    HIV;    Acquired Immunodeficiency Syndrome;    Survival Analysis;    Health Inequalities;    Transmissão Vertical de Doença;    HIV;    Síndrome de Imunodeficiência Adquirida;    Análise de Sobrevida;    Desigualdades em Saúde;   

DOI  :  10.1590/S0102-311X2007001500011

来源: SciELO

【 摘 要 】

Antiretroviral therapy contributes to decreasing morbidity and mortality, and ultimately to increasing survival. In Brazil, there are regional differences in HIV epidemiology regarding pregnant women and children with HIV/AIDS. This study evaluates survival time after AIDS diagnosis in 914 children infected by mother-to-child transmission, reported between 1983 and 1998 and followed until 2002, in Brazil's five regions. Time between birth and HIV diagnosis decreased over the years, mainly in the South and Southeast Regions. There was a significant improvement in survival; more than 75% of cases were still living four years after diagnosis in the 1997-1998 group. This Brazilian study demonstrates that even with regional inequalities in health care infrastructure it is possible for a developing country to establish an effective system of universal and free access to antiretroviral therapy that produces a significant increase in survival for children with AIDS.

【 授权许可】

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