Química Nova | |
Análise térmica aplicada a fármacos e formulações farmacêuticas na indústria farmacêutica | |
Marcelo Antonio De Oliveira2  Maria Irene Yoshida1  Elionai Cassiana De Lima Gomes1  | |
[1] ,Universidade Federal do Espírito Santo Centro Universitário Norte do Espírito Santo São Mateus ES ,Brasil | |
关键词: thermal analysis; pharmaceutical industry; characterization; | |
DOI : 10.1590/S0100-40422011000700022 | |
来源: SciELO | |
【 摘 要 】
Several matters of the pharmaceutical demonstrate the great importance of thermal analysis application, especially TG and DSC for the pharmaceutical industry future, namely: characterization of the drugs with the thermal events definition, in studies of drug purity, in the polymorphs identification, in compatibility studies of solid dosage pharmaceutical formulations, in drugs and pharmaceutical formulations thermal stability, and in determination of shelf life for isothermal degradation kinetics by extrapolation using the Arrhenius equation. Thus, the test results obtained from thermal analysis are directly related to the quality of a pharmaceutical product, whether the stability or bioavailability of the pharmaceutical product.
【 授权许可】
CC BY-NC
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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