Química Nova | |
Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase | |
Carlos Areche2  Patricia Cejas2  Pablo Thomas2  Aurelio San-martín2  Luis Astudillo1  Margarita Gutiérrez1  Luis A Loyola1  | |
[1] ,University of Chile Faculty of Sciences Department of ChemistrySantiago,Chile | |
关键词: Azorella; Umbelliferae; triterpenes; | |
DOI : 10.1590/S0100-40422009000800008 | |
来源: SciELO | |
【 摘 要 】
The inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with two mulinane-type diterpenes were isolated from petroleum ether extract of the whole shrub of Azorella trifurcata (Gaertn.) Pers. Their effect on the enzyme acetylcholinesterase was assessed as well. In addition, this is the first report of these triterpenes in the genus Azorella.
【 授权许可】
CC BY-NC
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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