期刊论文详细信息
Quimica nova | |
Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase | |
Loyola, Luis A1  Thomas, Pablo2  Cejas, Patricia2  San-Martín, Aurelio2  Areche, Carlos2  Astudillo, Luis3  Gutiérrez, Margarita3  | |
[1] University of Antofagasta, Antofagasta, Chile;University of Chile, Santiago, Chile;University of Talca, Talca, Chile | |
关键词: Azorella; Umbelliferae; triterpenes.; | |
DOI : 10.1590/S0100-40422009000800008 | |
学科分类:化学(综合) | |
来源: Sociedade Brasileira de Quimica | |
【 摘 要 】
The inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with two mulinane-type diterpenes were isolated from petroleum ether extract of the whole shrub of Azorella trifurcata (Gaertn.) Pers. Their effect on the enzyme acetylcholinesterase was assessed as well. In addition, this is the first report of these triterpenes in the genus Azorella.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201902012273693ZK.pdf | 191KB | download |