期刊论文详细信息
Química Nova | |
Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase | |
University of Chile, Santiago, Chile1  Thomas, Pablo1  Astudillo, Luis1  Cejas, Patricia1  Gutiérrez, Margarita1  Loyola, Luis A1  San-Martín, Aurelio1  University of Talca, Talca, Chile1  University of Antofagasta, Antofagasta, Chile1  Areche, Carlos1  | |
关键词: Azorella; Umbelliferae; triterpenes.; | |
DOI : 10.1590/S0100-40422009000800008 | |
学科分类:化学(综合) | |
来源: Sociedade Brasileira de Quimica | |
【 摘 要 】
The inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with two mulinane-type diterpenes were isolated from petroleum ether extract of the whole shrub of Azorella trifurcata (Gaertn.) Pers. Their effect on the enzyme acetylcholinesterase was assessed as well. In addition, this is the first report of these triterpenes in the genus Azorella.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912050594685ZK.pdf | 191KB | download |