Investigação do potencial antioxidante e anticolinesterásico de Hippeastrum (Amaryllidaceae)

Química Nova

Raquel Brandt Giordani²  Letícia Balvedi Pagliosa²  Amélia T. Henriques²  José Angelo S. Zuanazzi²  Julie H. A. Dutilh¹ 

[1] ,Universidade Federal do Rio Grande do Sul Faculdade de Farmácia Porto Alegre RS ,Brasil

关键词: Amaryllidaceae;    antioxidant;    anticholinesterasic;   

DOI  :  10.1590/S0100-40422008000800024

来源: SciELO

【 摘 要 】

Amaryllidaceae family is an important source of bioactive molecules and considering the taxonomic relationships, it is relevant to investigate the genus Hippeastrum. Thus, the aim of this work was to determine antioxidant and anticholinesterasic activities of Hippeastrum morelianum, Hippeastrum psittacinum and Hippeastrum santacatarina. Both antioxidant and acetylcholinesterasic activities of extracts were determinated by bioautography as 10 mg/mL and 0.1 mg/mL, respectively. The antioxidant activity of alkaloid lycorine, determinated spectrophotometrically with DPPH, indicated an IC50 value of 0.326 mM.

【 授权许可】

CC BY-NC   
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