Antioxidant and anticolinesterasic effects of Hippeastrum species (Amaryllidaceae)

Quimica nova

Dutilh, Julie H. A.¹  Pagliosa, Letícia Balvedi²  Henriques, Amélia T.²  Giordani, Raquel Brandt²  Zuanazzi, José Angelo S.² 

[1] Universidade Estadual de Campinas, Campinas, Brasil;Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil

关键词: Amaryllidaceae;    antioxidant;    anticholinesterasic.;   

DOI  :  10.1590/S0100-40422008000800024

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Amaryllidaceaefamily is an important source of bioactive molecules and considering the taxonomicrelationships, it is relevant to investigate the genus Hippeastrum. Thus,the aim of this work was to determine antioxidant and anticholinesterasic activitiesof Hippeastrum morelianum, Hippeastrum psittacinum and Hippeastrumsantacatarina. Both antioxidant and acetylcholinesterasic activities ofextracts were determinated by bioautography as 10 mg/mL and 0.1 mg/mL, respectively.The antioxidant activity of alkaloid lycorine, determinated spectrophotometricallywith DPPH, indicated an IC50 value of 0.326 mM.

【 授权许可】

CC BY