Two New Alkaloids from Narcissus serotinus L.

Molecules

Natalia B. Pigni¹  Strahil Berkov¹  Abdelaziz Elamrani¹  Mohammed Benaissa¹  Francesc Viladomat¹  Carles Codina¹ 

[1] ¹Department of Natural Products, Plant Biology and Soil Science, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain ²Department of Chemistry, Faculty of Sciences Ain Chock, University Hassan II, Casablanca, Morocco

关键词: Narcissus serotinus;    Amaryllidaceae;    alkaloids;    narseronine;    1-O-(3´-acetoxy-butanoyl)lycorine;   

DOI  :  10.3390/molecules15107083

来源: mdpi

【 摘 要 】

The Amaryllidaceae family is well known for the presence of an exclusive group of alkaloids with a wide range of biological activities. Narcissus serotinus L. is a plant belonging to this family and its geographical distribution is mainly located along the Mediterranean coast. In the present work, specimens collected near Casablanca (Morocco) were used to study the alkaloid content of this species. Starting with 350 g of the whole plant we used standard extraction and purification procedures to obtain fractions and compounds for GC-MS and NMR analysis. As well as five known alkaloids, we isolated two new compounds: 1-O-(3´-acetoxybutanoyl)lycorine and narseronine. The latter has been previously published, but with an erroneous structure.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.