The genetic diversity of Plasmodium vivax: a review

Memórias do Instituto Oswaldo Cruz

Wanessa Christina De Souza-neiras²  Luciane Moreno Storti De Melo²  Ricardo Luiz Dantas Machado¹ 

[1] ,Universidade Estadual Paulista Instituto de Biociências, Letras e Ciências Exatas Departamento de BiologiaSão José do Rio Preto SP ,Brasil

关键词: malaria;    Plasmodium vivax;    genetic diversity;    molecular markers;    phylogeny;    evolution;   

DOI  :  10.1590/S0074-02762007000300002

来源: SciELO

【 摘 要 】

The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License