Antimicrobial activity of Hyptis ovalifolia towards dermatophytes

Memórias do Instituto Oswaldo Cruz

Lúcia Kh Souza²  Cecília Ma De Oliveira¹  Pedro H Ferri¹  Juldásio Galdino De Oliveira Júnior²  Ary Henrique De Souza Júnior²  Orionalda De Fátima Lisboa Fernandes²  Maria Do Rosário R Silva² 

[1] ,Instituto de Patologia Tropical e Saúde Pública Laboratório de Micologia

关键词: dermatophytes;    Hyptis ovalifolia;    antifungal activity;   

DOI  :  10.1590/S0074-02762003000700018

来源: SciELO

【 摘 要 】

The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration of £ 500 µg/ml.

【 授权许可】

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