Journal of the Brazilian Chemical Society | |
Chemical composition and antifungal activity of the essential oil of Hyptis ovalifolia Benth. (Lamiaceae) | |
Cecília M. A. De Oliveira2  Maria Do Rosário R. Silva1  Lucília Kato2  Cleuza C. Da Silva1  Heleno D. Ferreira1  Lúcia K. H. Souza1  | |
[1] ,Universidade Federal de Goiás Instituto de Química Goiânia GO ,Brazil | |
关键词: Hyptis ovalifolia; essential oil; antifungal activity; Lamiaceae; (R)-6-[(Z)-1-heptenyl]-5; 6-dihydro-2H-pyran-2-one; | |
DOI : 10.1590/S0103-50532004000500023 | |
来源: SciELO | |
【 摘 要 】
The leaves of Hyptis ovalifolia Benth. (Lamiaceae) were subjected to hydrodistillation and the resulting volatiles were investigated by GC/MS. The main constituent representing 60% of the essential oil was isolated by column chromatography and identified by spectroscopic methods as (R)-6-[(Z)-1-heptenyl]-5,6-dihydro-2H-pyran-2-one (1). This compound showed strong in vitro activity against four dermatophyte fungi Microsporum canis, Microsporum gypseum, Tricophyton mentagrophytes, and Tricophyton rubrum (a total of 60 strains) with a minimal inhibitory concentration observed in the range of 125-7.8 mg µL-1.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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