Rabies virus infection of cultured adult mouse dorsal root ganglion neurons

Memórias do Instituto Oswaldo Cruz

Jaime Castellanos¹  Hernán Hurtado²  Janeth Arias¹  Alvaro Velandia¹ 

[1] ,Instituto Nacional de Salud Laboratorio de Neurobiología Bogotá,Colombia

关键词: adult mouse;    cell culture;    dorsal root ganglion;    infection;    neuron;    neurotropism;    rabies;   

DOI  :  10.1590/S0074-02761996000500014

来源: SciELO

【 摘 要 】

An in vitro model of adult dorsal root ganglion neurons infection by rabies virus is described. Viral marked neurotropism is observed, and the percentage and the degree of infection of the neurons is higher than in non neuronal cells, even if neurons are the minority of the cells in the culture. The neuritic tree is also heavily infected by the virus.

【 授权许可】

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