Jornal Brasileiro de Psiquiatria | |
Effects of bariatric surgery on the central nervous system and eating behavior in humans: a systematic review on the neuroimaging studies | |
Hélio Tonelli2  Fernanda Mattias Sartori1  João Caetano Dallegrave Marchesini2  João Batista Marchesini2  Denise Gianoti Tonelli2  | |
[1] ,Clínica Marchesini | |
关键词: Neuroimaging; functional magnetic resonance; positron emission tomography; gastric bypass; bariatric surgery; Neuroimagem; imagem por ressonância magnética; tomografia por emissão de pósitrons; derivação gástrica; cirurgia bariátrica; | |
DOI : 10.1590/S0047-20852013000400007 | |
来源: SciELO | |
【 摘 要 】
INTRODUCTION: Neuroimaging studies suggest that obese people might show hyperactivity of brain areas regarding reward processing, and hypoactivity of brain areas concerning cognitive control, when exposed to food cues. Although the effects of bariatric surgery on the central nervous system and eating behavior are well known, few studies have used neuroimage techniques with the aim of investigating the central effects of bariatric surgery in humans. OBJECTIVES: This paper systematically and critically reviews studies using functional neuroimaging to investigate changes on the patterns of activation of central areas related to the regulation of eating behavior after bariatric surgery. METHOD: A search on the databases Medline, Web of Science, Lilacs and Science Direct on Line, was conducted in February 2013, using the keywords "Neuroimaging", "Positron-Emission Tomography", "Magnetic Resonance Imaging", "Gastric Bypass", "Gastroplasty", "Jejunoileal Bypass", "Bariatric Surgery". RESULTS: Seven manuscripts were included; the great majority studied the central effects of Roux en Y gastric bypass, using positron emission tomography or functional magnetic resonance. CONCLUSIONS: Bariatric surgery might normalize the activity of central areas concerned with reward and incentive salience processing, as the nucleus accumbens and mesencephalic tegmental ventral area, as well as circuitries processing behavioral inhibition, as the dorsolateral prefrontal cortex.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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