Larvicidal activity of oil-resin fractions from the Brazilian medicinal plant Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) against Aedes aegypti (Diptera, Culicidae)

Revista da Sociedade Brasileira de Medicina Tropical

Heloísa Helena Garcia Da Silva¹  Regina Geris²  Edson Rodrigues Filho²  Cleonice Rocha²  Ionizete Garcia Da Silva¹ 

[1] ,Universidade Federal de Goiás Instituto de Patologia Tropical e Saúde Pública Departamento de Microbiologia, Imunologia, Patologia e ParasitologiaGoiânia GO

关键词: Copaifera reticulata;    Aedes aegypti;    Terpenoids;    Larvicidal activity;    Copaifera reticulata;    Aedes aegypti;    Terpenoides;    Atividade larvicida;   

DOI  :  10.1590/S0037-86822007000300002

来源: SciELO

【 摘 要 】

Oil-resin fractions from Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) were evaluated for larvicidal activity on third larval instars of Aedes aegypti, in searching for alternative control methods for this mosquito. The bioactive fractions were chemically monitored by thin-layer chromatography, ¹H and 13C nuclear magnetic resonance and mass spectrometry. Bioassays were performed using five repetitions, at a temperature of 28 ± 1°C, relative humidity of 80 ± 5% and light and dark cycles of 12h. Mortality was indicated by darkening of the cephalic capsule after 24h of exposure of the larvae to the solutions. The most active fractions were CRM1-4 (sesquiterpenes) and CRM5-7 (labdane diterpenes), which showed LC50 values of 0.2 and 0.8ppm, respectively.

【 授权许可】

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