Larvicidal activity of oil-resin fractions from the Brazilian medicinal plant Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) against Aedes aegypti (Diptera, Culicidae)

Revista da Sociedade Brasileira de Medicina Tropical

Geris, Regina¹  Silva, Heloísa Helena Garcia da¹  Silva, Ionizete Garcia da¹  Rocha, Cleonice¹  Universidade Federal de São Carlos, São Carlos¹  Universidade Federal de Goiás, Goiânia¹  Rodrigues Filho, Edson¹  Universidade Católica de Goiás, Goiânia¹  Universidade Federal da Bahia, Salvador¹ 

关键词: Copaifera reticulata;    Aedes aegypti;    Terpenoids;    Larvicidal activity;   

DOI  :  10.1590/S0037-86822007000300002

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Oil-resin fractions from Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) were evaluated for larvicidal activity on third larval instars of Aedes aegypti, in searching for alternative control methods for this mosquito. The bioactive fractions were chemically monitored by thin-layer chromatography, 1H and 13C nuclear magnetic resonance and mass spectrometry. Bioassays were performed using five repetitions, at a temperature of 28 ± 1°C, relative humidity of 80 ± 5% and light and dark cycles of 12h. Mortality was indicated by darkening of the cephalic capsule after 24h of exposure of the larvae to the solutions. The most active fractions were CRM1-4 (sesquiterpenes) and CRM5-7 (labdane diterpenes), which showed LC50 values of 0.2 and 0.8ppm, respectively.

【 授权许可】

Unknown