Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru

Revista da Sociedade Brasileira de Medicina Tropical

Alan J. Magill²  Jorge Zegarra²  Coralith Garcia²  Wilmer Marquiño¹  Trenton K. Ruebush Ii¹ 

[1] ,Naval Medical Research Center DetachmentLima,Peru

关键词: Antimalarial drug resistance;    Plasmodium falciparum;    Sulfadoxine-pyrimethamine;    Mefloquine;    Peru;    Resistência a drogas antimalárica;    Plasmodium falciparum;    Sulfadoxina-pirimetamina;    Mefloquina;    Peru;   

DOI  :  10.1590/S0037-86822004000300015

来源: SciELO

【 摘 要 】

In vivo antimalarial drug efficacy studies of uncomplicated Plasmodium falciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.

【 授权许可】

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