Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru

Revista da Sociedade Brasileira de Medicina Tropical

National Center for Infectious Diseases¹  Magill, Alan J.¹  Zegarra, Jorge¹  Walter Reed Army Institute of Research, Silver Spring, USA¹  Instituto Nacional de Salud, Lima, Peru¹  Marquiño, Wilmer¹  Ruebush II, Trenton K.¹  Garcia, Coralith¹  Naval Medical Research Center Detachment, Lima, Peru¹ 

关键词: Antimalarial drug resistance;    Plasmodium falciparum;    Sulfadoxine-pyrimethamine;    Mefloquine;    Peru;   

DOI  :  10.1590/S0037-86822004000300015

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

In vivo antimalarial drug efficacy studies of uncomplicated Plasmodium falciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.

【 授权许可】

Unknown