CASE STUDY OF A PATIENT WITH HIV-AIDS AND VISCERAL LEISHMANIASIS CO-INFECTION IN MULTIPLE EPISODES

Revista do Instituto de Medicina Tropical de São Paulo

Elis Dionísio Da Silva¹  Luiz Dias De Andrade¹  Paulo Sérgio Ramos De Araújo¹  Vera Magalhães Silveira¹  Carlos Eduardo Padilha¹  Maria Almerice Lopes Da Silva¹  Zulma Maria De Medeiros¹ 

关键词: Co-infection;    Visceral leishmaniasis;    HIV infection;    AIDS;   

DOI  :  10.1590/S0036-46652013000600010

来源: SciELO

【 摘 要 】

SUMMARYReport of a 45-year-old male farmer, a resident in the forest zone of Pernambuco, who was diagnosed with human immunodeficiency virus (HIV) in 1999 and treated using antiretroviral (ARV) drugs. In 2005, the first episode of visceral leishmaniasis (VL), as assessed by parasitological diagnosis of bone marrow aspirate, was recorded. When admitted to the hospital, the patient presented fever, hepatosplenomegaly, weight loss, and diarrhea. Since then, six additional episodes of VL occurred, with a frequency rate of one per year (2005-2012, except in 2008). In 2011, the patient presented a disseminated skin lesion caused by the amastigotes of Leishmania, as identified by histopathological assessment of skin biopsy samples. In 2005, he was treated with N-methyl-glucamine-antimony and amphotericin B deoxycholate. However, since 2006 because of a reported toxicity, the drug of choice was liposomal amphotericin B. As recommended by the Ministry of Health, this report emphasizes the need for HIV patients living in VL endemic areas to include this parasitosis in their follow-up protocol, particularly after the first infection of VL.

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