Cross sectional study reveals a high percentage of asymptomatic Plasmodium vivax infection in the Amazon Rio Negro area, Brazil

Revista do Instituto de Medicina Tropical de São Paulo

Martha C. Suárez-mutis²  Patricia Cuervo²  Fabiana M.s. Leoratti¹  Sandra L. Moraes-avila¹  Antonio Walter Ferreira¹  Octavio Fernandes²  José Rodrigues Coura² 

[1] ,Instituto Oswaldo Cruz Departamento de Medicina Tropical Laboratório de Doenças ParasitariasRio de Janeiro RJ ,Brasil

关键词: Malaria;    Asymptomatic infection;    Plasmodium vivax;    Brazilian Amazon;   

DOI  :  10.1590/S0036-46652007000300005

来源: SciELO

【 摘 要 】

A parasitological, clinical, serological and molecular cross-sectional study carried out in a highly endemic malaria area of Rio Negro in the Amazon State, Brazil, revealed a high prevalence of asymptomatic Plasmodium vivax infection. A total of 109 persons from 25 families were studied in five villages. Ninety-nine inhabitants (90.8%) had at least one previous episode of malaria. Serology showed 85.7% and 46.9% of positivity when P. falciparum antigens and P. vivax MSP-1, respectively, were used. Twenty blood samples were PCR positive for P. vivax (20.4%) and no P. falciparum infection was evidenced by this technique. No individual presenting positive PCR reaction had clinical malaria during the survey neither in the six months before nor after, confirming that they were cases of asymptomatic infection. Only one 12 year old girl presented a positive thick blood smear for P. vivax. This is the first description of asymptomatic Plasmodium infection in this area studied.

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