Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations

Arquivos de Neuro-Psiquiatria

Tiago Machado Guerreiro¹  Danilo Ryuko Cândido Nishikawa¹  Lis Campos Ferreira¹  Hyder Aragão De Melo¹  Roberto César Pereira Do Prado¹ 

[1] ,Federal University of Sergipe

关键词: restless legs syndrome;    Parkinson's disease;    prevalence;    ferritin;    síndrome das pernas inquietas;    doença de Parkinson;    prevalência;    ferritina;   

DOI  :  10.1590/S0004-282X2010000600007

来源: SciELO

【 摘 要 】

Restless legs syndrome (RLS) is a neurological disorder that responds to dopaminergic drugs, indicating a common pathophysiology with Parkinson's disease (PD). The prevalence of RLS was estimated in a group of PD patients and its clinical and biochemical characteristics were analysed. Forty-eight patients with PD were evaluated into two groups, with and without RLS. Clinical characteristics assessed in both groups were age, gender, duration of PD, Hoehn and Yahr, and Schwab and England scales. Laboratory variables such as hemoglobin, s-iron, s-ferritin and creatinine were obtained. The prevalence of RLS was 18.75%. No significant differences regarding clinical variables and biochemical parameters were observed. The high prevalence of RLS found in PD patients suggests the concept of a common etiological link and it seems that secondary causes did not play a central role in the pathophysiology of RLS in this group of parkinsonian patients.

【 授权许可】

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