Brain SPECT in mesial temporal lobe epilepsy: comparison between visual analysis and SPM

Arquivos de Neuro-Psiquiatria

Bárbara Juarez Amorim²  Celso Darío Ramos²  Allan Oliveira Dos Santos²  Mariana Da Cunha Lopes De Lima²  Li Li Min¹  Edwaldo Eduardo Camargo²  Fernando Cendes¹  Elba Cristina Sá De Camargo Etchebehere² 

[1] ,Campinas State University School of Medical Sciences Department of RadiologyCampinas SP ,Brazil

关键词: brain perfusion;    SPECT;    SPM;    seizures;    epilepsy;    SPECT cerebral;    SPECT;    SPM;    crises;    epilepsia;   

DOI  :  10.1590/S0004-282X2010000200001

来源: SciELO

【 摘 要 】

OBJECTIVE: To compare the accuracy of SPM and visual analysis of brain SPECT in patients with mesial temporal lobe epilepsy (MTLE). METHOD: Interictal and ictal SPECTs of 22 patients with MTLE were performed. Visual analysis were performed in interictal (VISUAL(inter)) and ictal (VISUAL(ictal/inter)) studies. SPM analysis consisted of comparing interictal (SPM(inter)) and ictal SPECTs (SPM(ictal)) of each patient to control group and by comparing perfusion of temporal lobes in ictal and interictal studies among themselves (SPM(ictal/inter)). RESULTS: For detection of the epileptogenic focus, the sensitivities were as follows: VISUAL(inter)=68%; VISUAL(ictal/inter)=100%; SPM(inter)=45%; SPM(ictal)=64% and SPM(ictal/inter)=77%. SPM was able to detect more areas of hyperperfusion and hypoperfusion. CONCLUSION: SPM did not improve the sensitivity to detect epileptogenic focus. However, SPM detected different regions of hypoperfusion and hyperperfusion and is therefore a helpful tool for better understand pathophysiology of seizures in MTLE.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License