High Sensitivity SPECT for Small Animals and Plants

Mitchell, Gregory S.¹ 

[1] UC Davis

关键词: SPECT;    nuclear imaging;    plant imaging;   

DOI  :  10.2172/1171466
RP-ID  :  DOE-UCDAVIS-05311
PID  :  OSTI ID: 1171466

美国|英语

来源: SciTech Connect

【 摘 要 】

Imaging systems using single gamma-ray emitting radioisotopes typically implement collimators in order to form the images. However, a tradeoff in sensitivity is inherent in the use of collimators, and modern preclinical single-photon emission computed tomography (SPECT) systems detect a very small fraction of emitted gamma-rays (<0.3%). We have built a collimator-less system, which can reach sensitivity of 40% for 99mTc imaging, while still producing images of sufficient spatial resolution for certain applications in thin objects such as mice, small plants, and well plates used for in vitro experiments.